The 2001 GS 300 with the 2JZ-GE inline-six is mechanically solid, but the transmission cooler and VVT-i system are known weak points. The engine itself rarely fails catastrophically unless severely neglected or overheated, but high-mileage units can develop oil consumption issues.
Transmission Oil Cooler Line Failure
Common · high severityTypical onset: 80,000-150,000 mi
Symptoms: Pink or milky fluid in radiator or transmission, Transmission slipping or delayed engagement, Overheating transmission, Coolant or ATF leaking from radiator area
Fix: The factory cooler lines rust internally and leak into the radiator, mixing coolant and ATF—catastrophic for the A650E transmission. Must replace cooler lines, radiator (often contaminated), flush both systems completely, and sometimes replace transmission if contamination went unnoticed. 6-10 hours labor depending on transmission damage.
Estimated cost: $1,200-$4,500
VVT-i Cam Gear Oil Line Leak
Common · medium severityTypical onset: 100,000-180,000 mi
Symptoms: Oil seeping from timing cover area, Check engine light with VVT codes (P1349, P1354), Rough idle when cold, Oil consumption increase
Fix: The rubber O-rings on the VVT-i oil feed lines harden and leak. Requires timing cover removal, which means water pump and cam seals are usually done at the same time. 8-12 hours labor for thorough job including related preventive items.
Estimated cost: $1,800-$2,800
Lower Ball Joints and Control Arm Bushings
Common · medium severityTypical onset: 90,000-140,000 mi
Symptoms: Clunking over bumps, Wandering or imprecise steering, Uneven tire wear on inside edges, Play in front wheel when jacked up
Fix: The front lower control arms have non-serviceable ball joints that wear, and the rear bushings fail. Most shops replace entire arms rather than press bushings. Alignment required after. 3-4 hours per side, usually do both.
Estimated cost: $1,200-$1,800
Starter Motor Failure
Occasional · high severityTypical onset: 120,000-180,000 mi
Symptoms: Click but no crank, Intermittent no-start (works when cool, fails when hot), Grinding noise on startup, Slow cranking
Fix: The Denso starters develop worn contacts or solenoid issues. Tight access underneath with exhaust in the way. 2-3 hours labor, remanufactured starter recommended over cheap aftermarket.
Estimated cost: $600-$950
Alternator Failure
Occasional · medium severityTypical onset: 110,000-160,000 mi
Symptoms: Battery light on, Dimming lights or slow power windows, Voltage below 13.5V at idle, Whining or grinding from serpentine belt area
Fix: The Denso alternators eventually wear out, bearings fail or regulator goes. Straightforward R&R but proper load testing needed to confirm before replacement. 1.5-2 hours labor.
Estimated cost: $500-$800
Power Steering Pump Leak and Noise
Occasional · low severityTypical onset: 100,000-170,000 mi
Symptoms: Whining on cold starts or turning, Fluid leaking from pump or high-pressure line, Heavy steering feel, Groaning when turning at full lock
Fix: Pump seals leak or internal vanes wear. High-pressure line can also crack at crimps. Pump replacement is 2-3 hours; if doing lines too, add an hour. Use OEM-spec Dexron ATF, not generic PS fluid.
Estimated cost: $600-$1,100
Engine Oil Consumption (High-Mileage)
Occasional · medium severityTypical onset: 180,000+ mi
Symptoms: Blue smoke on cold start or deceleration, Oil level dropping 1 qt per 1,000-2,000 mi, Carbon buildup on tailpipes, Spark plugs oil-fouled
Fix: Valve stem seals harden or piston rings lose tension with age. Minor consumption (1 qt per 3,000 mi) is manageable; worse requires valve stem seals (head-off job, 12-16 hours) or full teardown for rings. Unless catastrophic, most owners just top off.
Estimated cost: $2,500-$6,000
Buy it if the transmission has been maintained and cooler lines already addressed—mechanically bulletproof otherwise, but avoid high-mileage examples with unknown maintenance history.
AI-assisted summary drawn from NHTSA recall data, our labor-times database, and platform knowledge. Not a substitute for a pre-purchase inspection on a specific vehicle.