The W140 S600 with the M120 V12 is a technological marvel that demands respect and deep pockets. When maintained properly it's incredibly robust, but deferred maintenance turns catastrophic fast—especially with the engine's well-documented wiring harness and biodegradable insulation issues.
Engine Wiring Harness Disintegration
Common · high severityTypical onset: 80,000-150,000 mi
Symptoms: Random misfires across multiple cylinders, Rough idle that comes and goes, Check engine light with multiple stored codes, Fuel smell in engine bay from cracked injector harness
Fix: Complete engine harness replacement is the only real fix. Mercedes used biodegradable insulation that turns to dust. Expect 18-25 hours labor to pull both harnesses (engine and injector). Aftermarket improved harnesses available. Do NOT attempt repairs—the insulation contaminates everything it touches.
Estimated cost: $3,500-5,500
Head Gasket Failure from Overheating
Occasional · high severityTypical onset: 100,000-180,000 mi
Symptoms: White smoke from exhaust on cold start, Coolant loss with no visible leaks, Rough running on one bank, Milky oil or oil in coolant reservoir
Fix: The M120 is an interference engine—overheating often warps heads. Both heads must come off (30-40 hours), get machined, and receive new gaskets. While you're in there, do valve stem seals, timing chain guides, and water pump. This is why you see so many 'engine rebuild' entries—once heads are off, smart owners go further.
Estimated cost: $6,000-9,000
Transmission Fluid Cooler and Mount Failures
Common · medium severityTypical onset: 90,000-140,000 mi
Symptoms: Transmission fluid in coolant or vice versa (pink milkshake in radiator), Harsh shifts or delayed engagement, Visible transmission sag on driver side, Clunking on acceleration from stop
Fix: The 722.633 transmission cooler lives inside the radiator and fails, cross-contaminating fluids—this kills transmissions. Mounts fail from age and V12 torque. Replace cooler/radiator as unit (6-8 hours), flush both systems multiple times. Mounts are 3-4 hours each. Do both sides preventatively.
Estimated cost: $1,800-3,200
Throttle Actuator Linkage Wear
Common · medium severityTypical onset: 70,000-120,000 mi
Symptoms: Rough or surging idle, Hesitation on light throttle, Intermittent limp mode, Idle hunts between 500-1000 RPM
Fix: The mechanical linkage between throttle actuators wears at pivot points. Both throttle bodies (one per bank) need linkage service or replacement. 4-6 hours labor. OE parts only—aftermarket fails quickly. Often misdiagnosed as MAF or idle control issues.
Estimated cost: $1,200-2,000
ABC Suspension Component Failures
Occasional · high severityTypical onset: 100,000-150,000 mi
Symptoms: Car sits low on one corner overnight, ABC warning light with 'Drive carefully' message, Hydraulic fluid leaks under car, Harsh ride or excessive body roll
Fix: Active Body Control is brilliant until it isn't. Struts, pump, and accumulator all fail. Front struts are 8-10 hours each, rears 6-8. Pump is 12-15 hours (under engine). Once one component fails, system stress accelerates other failures. Budget $3K-8K depending on what lets go. ABC fluid is special—$50/liter.
Estimated cost: $3,000-8,000
Vacuum System Leaks (Soft-close doors, HVAC, cruise)
Common · low severityTypical onset: 60,000-120,000 mi
Symptoms: Doors won't soft-close or pop back open, HVAC blend doors stuck or clicking, Cruise control inoperative, Central locking issues
Fix: The W140 uses vacuum for everything. Lines get brittle, check valves fail, reservoirs crack. Diagnosis takes longer than repair—smoke test is essential (3-5 hours total with repairs). Most common: door actuators ($200-400 each) and main supply line from pump.
Estimated cost: $800-1,800
Only buy if you have $5K-10K cushion for deferred maintenance, or full documented service history and strong mechanical aptitude—magnificent when sorted, financial nightmare otherwise.
AI-assisted summary drawn from NHTSA recall data, our labor-times database, and platform knowledge. Not a substitute for a pre-purchase inspection on a specific vehicle.