Every control module on the 2025 Mercedes-Benz E300 4MATIC All-Terrain — where it lives, replacement time, and what it takes to program a replacement. Modules marked dealer / factory tool won't work after a part swap alone — budget for programming.
Transmission Control Unit (TCU) 2.5 hr R&R security gateway +1.0 hr ▸ programming details
📍 Transmission bell housing, driver side
🔧 Xentry Diagnostics + SCN online
⚠️ 9G-TRONIC transmission. Requires transmission fluid change after replacement. VIN-locked SCN coding required.
Electric Power Steering Control Unit (EPS) 1.8 hr R&R security gateway +0.8 hr ▸ programming details
📍 Steering column, below instrument panel
🔧 Xentry Diagnostics + SCN online
⚠️ Steering angle sensor calibration required after replacement. VIN-locked.
Climate Control Unit (CCU) 1.8 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Dashboard, behind center HVAC controls
🔧 Xentry Diagnostics
⚠️ Dual-zone automatic climate control. Requires sensor calibration after replacement.
Night View Assist Control Unit (NVA) 1.5 hr R&R security gateway +0.8 hr ▸ programming details
📍 Front bumper, center behind grille
🔧 Xentry Diagnostics + SCN online
⚠️ Infrared night vision camera. Calibration required. VIN-locked. Optional equipment.
Electronic Stability Program Control Unit (ESP/ABS) 1.5 hr R&R security gateway +0.8 hr ▸ programming details
📍 Engine compartment, left front near fender
🔧 Xentry Diagnostics + SCN online
⚠️ Integrated hydraulic unit. Brake bleeding required after replacement. VIN-locked.
Central Gateway Module (CGW) 1.5 hr R&R security gateway +2.0 hr ▸ programming details
📍 Dashboard, behind center lower trim panel
🔧 Xentry Diagnostics + SCN online
⚠️ Security gateway. Replacement requires complete vehicle reconfiguration and all module re-authorization. Dealer-only procedure.
MBUX Head Unit (HU/MBUX) 1.5 hr R&R security gateway +0.8 hr ▸ programming details
📍 Dashboard, center stack
🔧 Xentry Diagnostics + SCN online
⚠️ 12.3-inch display. VIN-locked. Navigation and user settings require reconfiguration.
4MATIC Control Unit (4M) 1.5 hr R&R security gateway +0.8 hr ▸ programming details
📍 Transmission tunnel, center console area
🔧 Xentry Diagnostics + SCN online
⚠️ All-wheel drive control. VIN-locked. Requires test drive calibration after coding.
Motor Electronics / Engine Control Unit (ME/ECU) 1.2 hr R&R security gateway +1.0 hr ▸ programming details
📍 Engine compartment, left side firewall near brake master cylinder
🔧 Xentry Diagnostics + SCN online
⚠️ VIN-locked, requires online SCN authorization from Mercedes servers. EIS security triangle pairing mandatory.
Door Control Module - Passenger (DCM-P) 1.2 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Passenger door, inside door panel
🔧 Xentry Diagnostics
⚠️ Window control. Window initialization required after replacement.
Airmatic / Active Body Control Module (ADS/Airmatic) 1.2 hr R&R security gateway +0.8 hr ▸ programming details
📍 Rear cargo area, right side near spare tire well
🔧 Xentry Diagnostics + SCN online
⚠️ Air suspension control. Ride height calibration required after replacement. VIN-locked.
Rear Signal Acquisition and Actuation Module (SAM-R) 1.0 hr R&R security gateway +1.0 hr ▸ programming details
📍 Rear cargo area, left side panel
🔧 Xentry Diagnostics + SCN online
⚠️ Controls rear lighting, fuel pump relay, trailer functions. VIN-locked.
Camera Control Unit / Surround View (CCU) 1.0 hr R&R security gateway +0.8 hr ▸ programming details
📍 Rear cargo area, left side panel
🔧 Xentry Diagnostics + SCN online
⚠️ 360-degree camera system. Camera calibration required. VIN-locked.
Intelligent Light System Control Unit (ILS) 1.0 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Engine compartment, behind left headlight assembly
🔧 Xentry Diagnostics
⚠️ LED headlight control. Headlight aim calibration required after replacement.
Electronic Ignition Switch (EIS) 1.0 hr R&R security gateway +1.5 hr ▸ programming details
📍 Steering column, upper shroud
🔧 Xentry Diagnostics + SCN online
⚠️ Security triangle component (EIS-ECM-IC). Key programming and VIN-lock. All keys must be reprogrammed. Dealer-only.
Tailgate Control Module (TGM) 1.0 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Tailgate, inside tailgate panel
🔧 Xentry Diagnostics
⚠️ Power tailgate control. Position calibration required after replacement.
Parktronic Control Unit (PTS) 0.8 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Rear bumper, behind trim panel
🔧 Xentry Diagnostics
⚠️ Parking sensor system. Sensor calibration required after replacement.
Active Lane Keeping Assist Control Unit (ALKA) 0.8 hr R&R security gateway +0.8 hr ▸ programming details
📍 Windshield, behind rearview mirror
🔧 Xentry Diagnostics + SCN online
⚠️ Camera-based lane keeping. Windshield camera calibration required. VIN-locked.
Restraint Systems Control Unit (SRS) 0.8 hr R&R security gateway +0.8 hr ▸ programming details
📍 Center console, beneath center armrest
🔧 Xentry Diagnostics + SCN online
⚠️ VIN-locked. All airbag components must be recoded after replacement. Battery disconnect required.
Instrument Cluster (IC) 0.8 hr R&R security gateway +1.0 hr ▸ programming details
📍 Dashboard, behind steering wheel
🔧 Xentry Diagnostics + SCN online
⚠️ VIN-locked. Mileage programming requires dealer authorization. Part of EIS security triangle.
Fuel Pump Control Module (FPCM) 0.8 hr R&R dealer / factory tool +0.3 hr ▸ programming details
📍 Rear cargo area, under floor panel near fuel tank
🔧 Xentry Diagnostics
⚠️ Controls fuel pump operation. Basic adaptation required.
Trailer Module (TRM) 0.8 hr R&R dealer / factory tool +0.5 hr ▸ programming details
📍 Rear cargo area, left side panel
🔧 Xentry Diagnostics
⚠️ Trailer hitch electrical control. Optional equipment. Requires activation coding if added aftermarket.
Telematics Communication Module (TCM) 0.6 hr R&R security gateway +0.5 hr ▸ programming details
📍 Rear cargo area, right side panel
🔧 Xentry Diagnostics + SCN online
⚠️ LTE module for Mercedes me connect. Requires subscription activation after replacement.
Seat Control Module - Passenger (SCM-P) 0.6 hr R&R aftermarket tool +0.3 hr ▸ programming details
📍 Passenger seat, under seat frame
🔧 Xentry Diagnostics or Autel
⚠️ Memory seat functions. Seat position relearn required.
Aftermarket tool coverage varies by software version and vehicle build — treat "aftermarket tool" rows as "usually possible" and verify against your tool maker's coverage list before promising a customer. Spot a wrong location or hour?
Tell us — corrections ship fast here.