Fitment notes: AGM battery required for 48V mild hybrid system; located in trunk under floor panel
As an Amazon Associate and Autel/ANCEL partner, OLP earns from qualifying purchases — how we link. This never changes the specs we publish.
Every control module on the 2021-2025 Mercedes-Benz E450 W213 — where it lives, replacement time, and what it takes to program a replacement. Modules marked dealer / factory tool won't work after a part swap alone — budget for programming.
Transmission Control Unit (TCU)2.5 hr R&Rsecurity gateway +1.0 hr▸ programming details
⚠️ Controls fuel pump operation. Basic adaptation possible with aftermarket tools.
Intelligent Light System Control Unit (ILS)0.5 hr R&Rdealer / factory tool +0.3 hr▸ programming details
📍 Each headlight assembly (left and right modules)
🔧 Xentry Diagnostics
⚠️ LED or Digital Light headlights. 2021+ may have DIGITAL LIGHT. Requires coding and aim calibration.
Aftermarket tool coverage varies by software version and vehicle build — treat "aftermarket tool" rows as "usually possible" and verify against your tool maker's coverage list before promising a customer. Spot a wrong location or hour? Tell us — corrections ship fast here.
Size-standard part numbers — verify your connector type before buying. Rear blades are model-specific; check the package's vehicle list.
Fuel economy figures are EPA data via fueleconomy.gov (median across matching trims). Performance figures are compiled estimates for the 2025 Mercedes-Benz E450 W213 3.0L I6 Turbo M256 and can vary by trim.
🔧 Database maintained under the daily editorial review of Chris Hackleman · Master Technician · 20+ years.