6.0L V12 BiTurbo M275RWDAUTOMATICgasM275turbo
Founding sponsor spot is openYour name on every procedure for this vehicle, permanently.Sponsor — $99 →
electrical

Fuse Box - Engine Bay

for 2012 Mercedes-Benz S65 AMG 6.0L V12 BiTurbo M275 · RWD
Editorial review:Chris HacklemanMaster Technician · 20+ years · Jeff MooreMaster Mechanic · 20+ years
Difficulty
Moderate
Time
2.7 h
Tools
10
Steps
13
Expert-verified. Personally reviewed and approved by OLP's master technicians (Chris Hackleman & Jeff Moore — 20+ years each). Always follow the vehicle's factory service information and torque specs.

This procedure covers the removal and replacement of the engine bay fuse box (SAM module) on the 2007-2013 Mercedes-Benz S65 AMG with the 6.0L V12 BiTurbo M275 engine.

Warnings

⚠️Always disconnect battery negative terminal and wait 15 minutes before working on electrical components to prevent airbag deployment or electrical shock
The SAM module contains vehicle-specific programming and must be coded to the vehicle after installation using Mercedes-Benz diagnostic equipment
Do not force electrical connectors - the locking mechanisms are fragile and expensive to replace
ℹ️Document all fuse positions and relay locations with photos before removal for proper reinstallation

Tools required

As an Amazon Associate and Autel/ANCEL partner, OLP earns from qualifying purchases — how we link. This never changes the specs we publish.

Parts

As an Amazon Associate and Autel/ANCEL partner, OLP earns from qualifying purchases — how we link. This never changes the specs we publish.

Preparation

  1. Park vehicle on level ground and engage parking brake
  2. Turn ignition off and remove key fob from vehicle
  3. Allow engine to cool completely if recently operated
  4. Open hood and secure with prop rod
  5. Take detailed photos of fuse box and all electrical connections for reference
  6. Disconnect battery negative terminal and wait minimum 15 minutes before proceeding

Procedure

  1. 1
    Disconnect battery and remove cover
    Remove the battery negative terminal using a 10mm socket. Wait 15 minutes for system capacitors to discharge. Remove the engine cover by pulling upward on the four corners - it is secured by rubber grommets only.
    Torque spec
    Battery Terminal Bolts6 Nm (4 lb-ft)
  2. 2
    Remove fuse box cover
    Locate the engine bay fuse box on the left side of the engine bay near the firewall. Release the cover clips by pressing the tabs on both sides and lift the cover away. Remove the cover screws using a T25 Torx driver if present on your model year.
    Torque spec
    Cover Screws15 Nm (11 lb-ft)
  3. 3
    Document and remove fuses and relays
    Photograph the exact position of all fuses and relays. Remove all fuses and relays from the fuse box and store them in labeled containers or bags corresponding to their positions. Note that some high-current fuses may require significant force to extract.
    ℹ️High-current fuses (80A+) are press-fit and require firm, even pulling force to avoid bending terminals
  4. 4
    Disconnect electrical connectors
    Identify all multi-pin electrical connectors attached to the rear and sides of the fuse box (typically 3-5 large connectors). Press the locking tabs and carefully pull each connector straight out. Mark each connector position with tape and numbering for reinstallation. Some connectors have secondary locks that must be released first.
    The large brown connector has a sliding secondary lock that must be moved to the unlock position before the main connector can be released
  5. 5
    Remove ground connections
    Locate the ground strap(s) attached to the fuse box housing using 10mm bolts. Remove the ground strap bolts and disconnect all ground connections. Clean the contact surfaces with electrical contact cleaner.
    Torque spec
    Ground Strap Bolts12 Nm (9 lb-ft)
    Ground Bolt18 Nm (14 lb-ft)
  6. 6
    Remove mounting hardware
    Remove the fuse box mounting bolts using a 13mm socket. There are typically 2-3 mounting bolts securing the fuse box to the bracket on the fender well. Support the fuse box while removing the final bolt to prevent it from falling.
    Torque spec
    Module Mounting Bolts8 Nm (6 lb-ft)
  7. 7
    Extract fuse box assembly
    Carefully maneuver the fuse box out of its mounting location. It may be necessary to tilt or rotate the assembly to clear surrounding components. Be mindful of sharp edges on nearby heat shields and brackets. Inspect the mounting bracket for damage or corrosion.
    The fuse box may have additional wiring harness clips attached to its underside that must be released before full removal
  8. 8
    Transfer components to new fuse box
    If installing a new fuse box, transfer any removable modules, sensors, or brackets from the old unit to the new one. Ensure all module mounting bolts are properly torqued. Do NOT transfer fuses or relays yet.
    Torque spec
    Module Mounting Bolts8 Nm (6 lb-ft)
    Mounting Bolts46 Nm (34 lb-ft)
  9. 9
    Install new fuse box assembly
    Position the new or serviced fuse box into the mounting bracket, ensuring proper alignment with all mounting holes. Install mounting bolts finger-tight initially, then torque to specification in a cross-pattern.
    Torque spec
    Module Mounting Bolts8 Nm (6 lb-ft)
  10. 10
    Reconnect ground connections
    Reattach all ground straps to the fuse box housing. Ensure contact surfaces are clean and free of corrosion. Apply a thin layer of dielectric grease to prevent future corrosion. Torque ground bolts to specification.
    Torque spec
    Ground Strap Bolts12 Nm (9 lb-ft)
    Ground Bolt18 Nm (14 lb-ft)
  11. 11
    Reconnect electrical connectors
    Reconnect all multi-pin electrical connectors to their original positions using your reference photos. Ensure each connector clicks fully into place and that all locking tabs engage properly. Verify secondary locks are in the locked position.
    Each connector is keyed differently - do not force connectors into incorrect positions as this will damage pins
  12. 12
    Install fuses and relays
    Reinstall all fuses and relays to their original positions using your documentation photos. Ensure each fuse and relay is fully seated. High-current fuses should snap firmly into place.
    ℹ️Incorrect fuse placement can cause electrical system damage or component failure
  13. 13
    Reconnect battery and program module
    Reconnect the battery negative terminal and torque to specification. The vehicle will require programming/coding of the new SAM module using Mercedes-Benz XENTRY or Star Diagnostic System. This must be performed by a qualified technician with proper diagnostic equipment.
    ⚠️Vehicle will not function properly until SAM module is programmed with VIN-specific data and system configuration
    Torque spec
    Battery Terminal Bolts6 Nm (4 lb-ft)

Reassembly

  1. Reinstall fuse box cover and secure all clips
  2. Reinstall engine cover by aligning grommets and pressing down firmly
  3. Verify all tools and parts have been removed from engine bay
  4. Close hood and ensure proper latching

Verification

  • Confirm battery voltage is approximately 12.6V with engine off
  • Turn ignition to position 2 and verify all dash warning lights illuminate normally
  • Start engine and verify no new warning lights or fault messages appear
  • Test operation of all electrical systems: lights, windows, wipers, climate control, infotainment
  • Verify no electrical warning messages in instrument cluster
  • Perform test drive and confirm all vehicle systems function normally
  • Scan for fault codes using diagnostic equipment and verify proper SAM module communication
  • Verify all electrical consumers (headlights, HVAC, radio) function correctly

Related trouble codes on this vehicle

Codes that commonly send this job to the bay — tap one for symptoms, causes, and diagnostic steps.

Chasing one of these codes and not sure which part is guilty? Ask a master mechanic about YOUR car →

🔧Stuck on this fuse box - engine bay? Take it to The Diag Desk.A human with 20+ years in the bay answers about YOUR Mercedes-Benz within 24 hours — never AI. $25, and you're not charged unless you get an answer.Ask a tech →

More procedures for this vehicle

🔧 Database maintained under the daily editorial review of Chris Hackleman · Master Technician · 20+ years and Jeff Moore · Master Mechanic · 20+ years. Spot an error? Use the Help link above — a human reads every report.
Stuck on this repair? Take it to The Diag Desk — ask a master tech about this exact car → real human answer within 24h, never AI
⚠ STILL BEHIND THE PAYWALL
The 2012 Mercedes-Benz S65 AMG repair data is incomplete because no one has sponsored it yet. For $99, we generate the full step-by-step procedures, then fact-check them with a second AI pass and your expert review. Your name on every procedure, permanently.
The same data would cost $169/mo from Mitchell1 or $30/year from ALLDATAdiy — and you'd be renting access, not freeing it. Sponsor once, free forever.
Sponsor the Mercedes-Benz S65 AMG — $99 →
Building an app?
Free API access to all this data — 10 requests/day, no card required.
Get an API key →
Run a shop?
Manage repairs, estimates, and customers with ShopBase — $249/mo, all features included.
Try ShopBase →